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Tissue Procurement









Biofluids > Isolation < Tissues




Tissue Procurement
QUALITY TISSUE SOURCE (SPECIES)
  • Strict collection protocols
  • High quality procedure of manipulation and control
  • Validated by a board-licensed pathologist
  • Human
  • Animals (46 species)
  • Plants (38 species)
  • Cell lines
MEDICAL CONDITIONS TISSUE ORIGIN (ORGAN)
  • Normal - Healthy (415 main organs)
  • Cancer & Tumor (84 oncology areas )
  • Disease (125 therapeutics areas)
  • Most representation of organ systems
  • Different development stages
DONOR ETHNICITY AGE RANGE
  • African-American
  • Asian
  • Caucasian
  • Hispanic
  • Human Adult (18-60) and fetal
  • Animal adult and embryo
PROCUREMENT TYPE ADDITIONAL
  • Autopsy
  • Surgical
  • Consent form provided
  • Donor information provided


Tissue Procurement Chart
Tissue Biorepository


THE SERVICE PROVIDED BY AMSBIO
Services
Description
Tissues
  • Custom tissue collection (Matched pair tumor & NAT)
  • Histology service: processing/fixation/embedding tissues – Fresh – Frozen – OCT – paraffin
  • Tissue sectioning service; at any thickness (microtome/cryostat)
  • Tissue microarray creation service (variety of core number and size) and FDA Standard TMA
  • Validation of Cancer genes by NGS of cancer samples
  • Special staining service and immunostaining
  • Image digital capture of tissues
Biofluids
  • Blood, Bone Marrow, Broncheolar lavage (BAL), Cerebral Spinal fluid, Plasma, Serum, sputum, Synovial, Urine, etc
  • Different biofluids drawn under customer specific protocol
  • Subcellular fraction from blood can be prepared
DNA
  • DNA derived samples available: gDNA, small size gDNA, cDNA from tissue samples
  • DNA extraction from FFPE tissue samples
  • Next Generation Sequence analysis for DNA samples
  • Construction of Southern blotting service using DNA samples
RNA
  • We can isolate Total RNA, microRNA, mRNA
  • Universal RNA preparation as reference standards
  • Matched pair RNA samples can be provide, which include RNA isolated from tumor and it’s normal adjacent
  • DNA extraction from FFPE tissue samples
  • Next Generation Sequence analysis for RNA samples
  • Construction of Northern blotting service using total RNA and/or mRNA
Protein
  • We can provide total proteins lysates from tissues and cells
  • Construction of Western blotting service using total protein samples
  • Quantify and analyse protein by Elisa (direct sandwich)
  • Simultaneous isolation of DNA, RNA and Protein from the same source
Cells
  • We can culture and collect cells from culture plates
  • Fixation of cells provided by customer
  • Inclusion of cells pellet
  • Processing and embedding cell pellets
  • Sectioning cell pellet at any thickness
  • Subcellular fraction from blood can be prepared
  • PBMC, BMMC
  • Development of primary cell line from solid tumors and normal tissue
Additional
  • Pathology service: pathology lab service, evaluation of tumor tissues, consultation services
  • Imaging service: Low/high resolution scans


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AMS Biotechnology (Europe) Limited, 184 Park Drive, Milton Park, Abingdon OX14 4SE, UK.
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