Cas9 Inducible (Tet-On) iPS Cell Pool
Product Code
78845
$0.00
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The Cas9 Inducible (Tet-On) iPS Cell Pool expresses the Cas9 (Streptococcus pyogenes CRISPR associated protein 9) gene under the control of a tight TRE tetracycline-inducible promoter/ introduced into PBMC-derived human iPS cells via lentiviral transduction [Cas9 Lentivirus (inducible TET on)/ #78794]. Cas9 expression can be induced with doxycycline treatment/ allowing temporal control of its expression. Cas9 Inducible (Tet-On) iPS cells can be transduced with single-guide RNA (sgRNA) targeting gene(s) of interest to generate genetically engineered cell pools or cell lines.
SKU | 78845 |
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Size | 1 vial |
Application | • Study molecular pathways using temporally controlled induction of gene editing.• Generation of sgRNA-edited iPS cell pools.• Screening of pooled sgRNAs libraries to identify pluripotency/ differentiation/ and drug toxicity genetic modulators. |
Gene synonyms | iPSC |
Storage | Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. |
Shipping Temp | -80C (dry ice) |
Supplier Name | BPS |