GLP-1R/CRE Luciferase Reporter HEK293 Cell Line

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AMS.78176
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Recombinant HEK293 cells expressing firefly luciferase gene under the control of cAMP response element (CRE) with constitutive expression of human GLP-1R (Glucagon-like peptide 1 receptor; accession number BC113493).GLP-1R/ a member of the class B family of G protein-coupled receptors (GPCRs) primarily found in pancreatic beta cells/ is activated by a peptide hormone/ glucagon-like peptide 1 (GLP-1) that is secreted from intestinal L-cells after nutrient ingestion. GLP-1R plays an important role in controlling blood sugar level by enhancing glucose-stimulated insulin secretion/ so various research efforts have focused on the regulation of the GLP-1R mediated signaling pathway as a therapeutic approach to diabetes.
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SKU AMS.78176
Size 2 vials
Species Human
Application Screen for agonists of human GLP-1R in a cellular context
Gene synonyms lucagon-like peptide 1 receptor cell line, GLP-1 cells, GLP-1-R cell line, GLP-1R cells, glucagon like peptide 1 receptor cells
Storage Cells will arrive upon dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80C freezer for long term storage.
Shipping Temp -80C (dry ice)
Supplier Name BPS
For more details visit our GLP-1R, GIPR and GCGR cell lines for diabetes and obesity research page >