MDM2 TR-FRET Assay Kit

Name: MDM2 TR-FRET Assay Kit
Brand: AMS.79773
SKU: AMS.79773
Availability: InStock

Product Code

AMS.79773

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Overview

Human Casitas B-lineage lymphoma proto-oncogene b (MDM2) is an E3 ubiquitin-protein ligase that functions as a negative regulator of T-cell activation. It is a potential drug target in cancer immunotherapy. The MDM2 TR-FRET Assay Kit is designed to measure MDM2 auto-ubiquitination activity in a homogeneous 384 reaction format. It utilizes biotin-labeled ubiquitin and a terbium-labeled anti-GST antibody to complete the TR-FRET pairing. This FRET-based assay requires no time-consuming washing steps|making it especially suitable for high throughput screening applications.

Product Specifications

More Information
SKU	AMS.79773
Size	384 reactions
Application	Great for screening small molecular inhibitors for drug discovery and HTS applications.
Gene synonyms	Mdm2,mouse double minute 2, human homolog, Hdm2
Storage	At least 6 months from date of receipt when stored as directed.
Shipping Temp	-80C (dry ice)
Supplier Name	BPS

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MDM2 TR-FRET Assay Kit

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